Xavier Leleu Selected Research

Pneumonia (Pneumonitis)

1/2022	Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): follow-up analysis of a randomised, phase 3 study.
11/2021	Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised, open-label, phase 3 trial.
11/2020	Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial.
12/2019	Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study.
1/2019	Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma.

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Xavier Leleu Research Topics

Disease

155	Multiple Myeloma 05/2024 - 08/2002
45	Waldenstrom Macroglobulinemia (Macroglobulinemia) 08/2019 - 05/2006
44	Neoplasms (Cancer) 03/2024 - 10/2003
18	Disease Progression 02/2024 - 05/2008
9	Neutropenia 10/2023 - 01/2016
9	Paraproteinemias (Monoclonal Gammopathy) 03/2013 - 08/2007
7	Peripheral Nervous System Diseases (PNS Diseases) 10/2021 - 05/2011
7	Lymphoma (Lymphomas) 01/2021 - 01/2007
6	Venous Thromboembolism 12/2023 - 10/2013
6	Thrombocytopenia (Thrombopenia) 10/2023 - 01/2016
6	Infections 01/2021 - 01/2006
6	Anemia 01/2019 - 01/2006
6	Non-Hodgkin Lymphoma (Lymphosarcoma) 04/2013 - 02/2004
5	Residual Neoplasm 01/2023 - 12/2016
5	Pneumonia (Pneumonitis) 01/2022 - 01/2019
4	Frailty 01/2023 - 01/2020
4	Amyloidosis 10/2022 - 09/2012
4	Lymphopenia (Lymphocytopenia) 11/2021 - 01/2019
4	Immunoglobulin Light-chain Amyloidosis 10/2020 - 09/2007
4	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2019 - 10/2003
4	Monoclonal Gammopathy of Undetermined Significance 10/2017 - 10/2005
3	Sepsis (Septicemia) 10/2023 - 12/2019
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2023 - 01/2016
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2021 - 01/2018
3	Cytopenia 08/2014 - 06/2008
3	Leukemia 12/2010 - 01/2009
2	Renal Insufficiency (Renal Failure) 12/2023 - 01/2006
2	Hemorrhage 12/2023 - 01/2019
2	Urinary Tract Infections (Urinary Tract Infection) 01/2022 - 12/2019
2	Smoldering Multiple Myeloma 01/2022 - 03/2016
2	Pain (Aches) 10/2021 - 06/2013
2	Fatigue 11/2020 - 01/2016
2	Agammaglobulinemia (Hypogammaglobulinemia) 01/2019 - 06/2008
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019 - 10/2003
2	Febrile Neutropenia 01/2019 - 03/2018
2	Plasmacytoma 01/2018 - 05/2011
2	Plasma Cell Leukemia 01/2016 - 12/2015
2	Carcinogenesis 01/2014 - 09/2002

Drug/Important Bio-Agent (IBA)

78	Dexamethasone (Maxidex)FDA LinkGeneric 05/2024 - 11/2006
46	Lenalidomide (CC 5013)FDA Link 04/2024 - 01/2009
44	Bortezomib (Velcade)FDA Link 05/2024 - 11/2006
23	carfilzomibIBA 02/2024 - 05/2015
20	pomalidomideIBA 05/2024 - 03/2013
20	Immunoglobulin M (IgM)IBA 10/2017 - 08/2007
19	daratumumabIBA 02/2024 - 01/2019
17	Proteasome InhibitorsIBA 04/2024 - 04/2009
16	isatuximabIBA 05/2024 - 12/2019
14	Proteins (Proteins, Gene)FDA Link 04/2023 - 11/2006
14	Thalidomide (Thalomid)FDA Link 10/2021 - 08/2002
13	Monoclonal AntibodiesIBA 02/2024 - 05/2006
13	Immunomodulating AgentsIBA 12/2023 - 10/2012
13	Melphalan (Alkeran)FDA LinkGeneric 01/2022 - 03/2007
9	Immunoglobulins (Immunoglobulin)IBA 01/2019 - 01/2006
8	selinexorIBA 05/2024 - 11/2020
8	ixazomibIBA 04/2024 - 05/2018
7	Prednisone (Sone)FDA LinkGeneric 01/2019 - 02/2004
7	Rituximab (Mabthera)FDA Link 11/2017 - 01/2007
5	belantamab mafodotinIBA 05/2024 - 10/2021
5	melflufenIBA 08/2022 - 10/2020
4	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 10/2023 - 01/2020
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023 - 02/2004
4	Immunologic Factors (Immunomodulators)IBA 09/2021 - 08/2007
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 02/2004
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019 - 05/2008
4	MicroRNAs (MicroRNA)IBA 01/2017 - 04/2009
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 02/2024 - 11/2006
3	Immunoconjugates (Immunoconjugate)IBA 10/2023 - 01/2020
3	elotuzumabIBA 01/2023 - 06/2012
3	Biomarkers (Surrogate Marker)IBA 12/2021 - 02/2011
3	Peptides (Polypeptides)IBA 10/2021 - 10/2020
3	Alkylating AgentsIBA 01/2021 - 03/2018
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 01/2018
3	NF-kappa B (NF-kB)IBA 04/2013 - 05/2008
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 08/2007 - 11/2006
2	Surface Antigens (Surface Antigen)IBA 01/2024 - 05/2006
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2023 - 07/2014
2	Immunoglobulin IsotypesIBA 10/2021 - 09/2002
2	AminopeptidasesIBA 01/2021 - 10/2020
2	Drug CombinationsIBA 11/2020 - 09/2014
2	ResveratrolIBA 08/2019 - 03/2008
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 03/2018 - 01/2016
2	Immunoglobulin G (IgG)IBA 01/2017 - 01/2007
2	Vorinostat FDA Link 01/2016 - 05/2013
2	Amyloid (Amyloid Fibrils)IBA 08/2015 - 12/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2014 - 10/2007
2	Antineoplastic Agents (Antineoplastics)IBA 08/2013 - 05/2008
2	ParaproteinsIBA 04/2013 - 04/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2013 - 02/2008

Therapy/Procedure

79	Therapeutics 05/2024 - 06/2007
17	Stem Cell Transplantation 11/2021 - 11/2006
10	Transplantation 03/2024 - 05/2012
10	Drug Therapy (Chemotherapy) 11/2021 - 09/2002
4	Immunotherapy 01/2024 - 12/2010
3	Subcutaneous Injections 12/2012 - 12/2008
3	Intravenous Administration 12/2012 - 12/2008
3	Aftercare (After-Treatment) 09/2009 - 02/2004
2	Hematopoietic Stem Cell Transplantation 03/2024 - 09/2007
2	Intravenous Infusions 02/2024 - 05/2011
2	Radiotherapy 01/2016 - 06/2013
2	Autologous Transplantation 08/2014 - 01/2014